Poster Presentations

1.

Secondary NMR Analysis of Estrogen Receptor Positive Breast Cancer: Diagnosis, Histology, and Years-to-Relapse Prediction.

Morris A. Aguilar, BS(1,2), Molly A. Hall, PhD, MS(1,2)  

1. Huck Institutes of the Life Sciences, The Pennsylvania State University 2. Department of Veterinary and Biomedical Sciences, The Pennsylvania State University 

2.

In silico Screening of Some Natural Products for Their Antiglycating Potential

Aparna Patil, MSc(1), Ahmad Ali, PhD(2) 1. G N Khalsa College, Mumbai, India  2. Department of Life Sciences, University of Mumbai, Indian

3.

Cell Ecosystem and Signaling Pathways of Primary and Metastatic Pediatric Posterior Fossa Ependymoma

Aubin, Rachael G., BS,  Troisi, Emma C., BS,  Alghalith, Adam N., B.S., Nasrallah, MacLean P., MD, PhD, Santi, Mariarita MD PhD,  Camara, Pablo G., PhD  University of Pennsylvania

4.

Inference of epistasis and the role of correlated mutations in determining the fitness landscape and entrenchment of drug resistance in HIV

Avik Biswas(1,2), Allan Haldane(1,2), Ronald M. Levy(1,2,3) 1. Center for Biophysics and Computational Biology,

2. Department of Physics, 3. Department of Chemistry, Temple University

5.

Multi-trait GWAS of Atherosclerosis and Correlated Traits Detects Novel Pleiotropic Loci

William P. Bone(1)*, Tiffany R. Bellomo(2)*, Derek Klarin(3,4,5,6), Julie A. Lynch(7,8), Themistocles L. Assimes(9,10), Michael Gaziano(11,12), the VA Million Veteran Program, Chris J. O'Donnell(13,12), Kyong-Mi Chang(14,15), Philip S. Tsao(9,10), Daniel J. Rader(15,16,17), Marylyn D. Ritchie(16,18,19), Scott M. Damrauer(14,2)**,

Benjamin F. Voight, PhD(14,16,18,20,21)**  1.Genomics and Computational Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania  2. Department of Surgery, Perelman School of Medicine, University of Pennsylvania  3.VA Boston Healthcare System 4. Center for Genomic Medicine, Massachusetts General Hospital 5. Division of Vascular Surgery and Endovascular Therapy, University of Florida School of Medicine 6. Department of Surgery, Massachusetts General Hospital 7. VA Informatics and Computing Infrastructure, VA Salt Lake City Health Care System  8. University of Massachusetts College of Nursing and Health Sciences 9. VA Palo Alto Health Care System 10. Department of Medicine, Stanford University 11. Massachusetts Veterans Epidemiology Research and Information Center, Veterans Affairs Boston Healthcare System 12.Department of Medicine, Brigham Women's Hospital 13. VA Boston Healthcare System 14. Corporal Michael J. Crescenz VA Medical Center, 15. Department of Medicine, University of Pennsylvania 16. Department of Genetics, University of Pennsylvania 17. Department of Pediatrics, University of Pennsylvania  18. Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania 19. Center for Precision Medicine, Perelman School of Medicine, University of Pennsylvania  20. Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania  21. Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania * These authors contributed equally  ** These authors jointly supervised this work

6.

An Investigation of the Pleiotropy between Type 2 Diabetes and Alzheimer's Disease 

Abigail Bossa (1) William Bone (2), Binglan Li (2), Marylyn D. Ritchie (2,3,4)    1. Long Island University 2. Genomics and Computational Biology Program, University of Pennsylvania 3. Department of Genetics, University of Pennsylvania 4. Institute for Biomedical Informatics, University of Pennsylvania

7.

perGeno, a Proteogenomic Tool for Precision Medicine

Xiaolong Cao, PhD,  Jinchuan Xing, PhD  Department of Genetics, Rutgers, the State University of New Jersey

8.

Genomic Data Augmentation Empowered with Generative Adversarial Networks

Junjie Chen, PhD,  Xinghua Shi, PhD  Temple University

9.

Small Noncoding RNA Profiles: It's More Personal Than You Think

Tess Cherlin,  Rogan Magee, PhD,  Yi Jing, PhD, Venetia Pliatsika, MS,  Phillipe Loher, MS,  Isidore Rigoutsos, PhD,

Thomas Jefferson University

10.

Patterns of Metabolic Reprogramming in the Post-hatch Broiler Chick as Characterized by Integration of Liver and Plasma-Derived High-Throughput Data

Heidi A. Van Every, PhD Candidate(1), Carl J. Schmidt, PhD(2) 1. Center for Bioinformatics and Computational Biology, University of Delaware  2.Department of Animal and Food Sciences, University of Delaware

11.

Apolipoprotein E ε4 Variant Alters Astrocytic Cytokine Secretion During Alzheimer's Disease Stimulus

Rebecca M Fleeman (1,2),  Madison K Kuhn (1,2,3),  Elizabeth A Proctor, PhD (1,2,3,4)    1. Departments of Neurosurgery and Pharmacology, Pennsylvania State College of Medicine  2. Center for Neural Engineering, Pennsylvania State University  3. Department of Biomedical Engineering, Pennsylvania State University 4. Department of Engineering Science & Mechanics, Pennsylvania State University

12.

Bioinformatic Analysis of Metagenomic Libraries Reveals the Impact of Early Feeding on the Infant Gut Microbiome

Matthew D. Di Guglielmo MD PhD (1), Karl Franke PhD (2), Brittni Deadrick BA (3), Erin L. Crowgey PhD ()]  1. Division of General Pediatrics, Department of Pediatrics, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA  2. Biomedical Research Department, Nemours Alfred I. duPont Hospital for Children, Wilmington, DE  3. Department of Pediatrics, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE

13.

Partition Quantitative Assessment (PQA): A Quantitative Methodology to Assess the Embedded Noise in Clustered Omics Data

Camacho-Hernández Diego A. BSc (1,2), Nieto-Caballero Victor E. BSc (1,2), and Freyre-González PhD, Julio A.(1) 1.Regulatory Systems Biology Research Group, Laboratory of Systems and Synthetic Biology, Center for Genomic Sciences, Universidad Nacional Autónoma de México (UNAM), Morelos, Mexico.  2. Undergraduate Program in Genomic Sciences, Center for Genomic Sciences, Universidad Nacional Autónoma de México (UNAM), Morelos, Mexico. 

14.

Epigenetic Encoding, Heritability and Plasticity of Glioma Transcriptional Cell States

Federico Gaiti, Ronan Chaligne, Dana Silverbush, Joshua S. Schiffman, Hannah R. Weisman, Lloyd Kluegel, Simon Gritsch, Sunil D. Deochand, Alyssa R. Richman,  Johanna Klughammer, Tommaso Biancalani, Christoph Muus, Caroline Sheridan, Alicia Alonso, Franco Izzo, Orit Rozenblatt-Rosen, Aviv Regev, Mario L. Suvà & Dan A. Landau   Weill Cornell Medicine

15.

annoFuse and shinyFuse: an R Package and Web Application to Annotate, Prioritize, and Interactively Explore Putative Oncogenic RNA Fusions

Krutika S. Gaonkar, MS(1,2,3), Federico Marini,PhD(4,5) , Komal S. Rathi,MS(1,2,3), Payal Jain,PhD(1,3) ,  Yuankun Zhu,MS(1,3), Nicholas A. Chimicles(1,2), Miguel A. Brown, MS(1,3), Ammar S. Naqvi, PhD(1,2,3) , Bo Zhang, MS(1,3), Phillip B. Storm, MD(1,3),  John M. Maris, MD(6), Pichai Raman, PhD(1,2,3), Adam C. Resnick, PhD(1,2,3), Konstantin Strauch(4), Jaclyn N. Taroni, PhD(7)*,  Jo Lynne Rokita, PhD(1,2,3)*     1.Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia 2.Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia 3.Division of Neurosurgery, Children's Hospital of Philadelphia  4.Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz  5.Center for Thrombosis and Hemostasis, Mainz, Germany  6. Division of Oncology, Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania 7.Alex's Lemonade Stand Foundation Childhood Cancer Data Lab

16.

Predicting Novel Kinase-substrate Interactions Using Graph Representation Learning.

Sachin Gavali, BDS(1), Chuming Chen, PhD(1), Karen Ross PhD(2), Julie Cowart, MS, PSM(1), and Cathy H. Wu, PhD(1,2)  

1. University of Delaware  2. Georgetown University Medical Center 

17.

Investigating The Unique Transcriptional Response Of Moraxella Catarrhalis "Rupture" Strains In Co-culture With Host Cells

Gordon, E.A., Earl, J., PhD, Ehrlich, R., MS,  Mell, J. C., PhD, Drexel University College of Medicine  

18.

Identifying Deleterious Variants Within Overgrowth Syndromes Related Genes in Pediatric Brain Tumor Patientsʼ Germline Genomic Data

Yiran Guo, PhD, Adam Resnick, PhD, Center for Data Driven Discovery in Biomedicine, Children's Hospital of Philadelphia

19.

Hi-C Analysis in Practice: A Workflow to Enhance our Understanding of the 3D Organization of the Genome

Katharina Hayer(1), Brittney Allyn(1), Craig Bassing, PhD(1) Eugene Oltz, PhD(2) 1. Department of Pathology and Laboratory Medicine | Division of Cancer Pathobiology, Children's Hospital of Philadelphia  2. The Ohio State University, Columbus Ahmet Sacan, PhD, School of Biomedical Engineering, Science & Health Systems, Drexel University, Philadelphia  

20.

METTL10 is a Kidney Disease Risk Gene by Altering Protein Methylation

Hailong Hu, Katalin Susztak. Renal Electrolyte and Hypertension Division, Department of Medicine and Genetics, University of Pennsylvania

21.

Uncovering the Mesendoderm Gene Regulatory Network Through Multi-omic Data Integration

Camden Jansen(1), Kitt D. Paraiso(1), Jeff J. Zhou(1), Ira L. Blitz(1), Michael W. Klymkowsky(2),   Masanori Taira(3), Gert J. Veenstra(4), Aaron M. Zorn(5), Ali Mortazavi(1), Ken W.Y. Cho(1 )  1. University of California, Irvine  2. University of Colorado, Boulder  3. University of Tokyo  4. Radboud Institute for Molecular Life Sciences  5. Cincinnati Children's Hospital Medical Center

22.

Patterns of Genetic Variant Combinations Determine the Phenotypic Trajectory of Neurodevelopmental Disorders. 

Matthew Jensen, BA(1),  Lucilla Pizzo, PhD(1), Anastasia Tyryshkina, BS(1), Corrine Smolen, MS(1), Laura Rohan, BS(1), Emily Huber, BS(1) , Maitreya Das, MS(1), Vijay Kumar Pounraja, MS(1),  Cora M. Taylor, MS(2) ; 16p12.1 Deletion Consortium; Santhosh Girirajan, MBBS, PhD(1) 1. Pennsylvania State University 2. Geisinger Health System

23.

Development and Application of Methods to Classify Clp Protease Protein Paralogs in Actinobacteria

Jialiu Jiang(1), Karl Schmitz, PhD(2)  1. Department of Chemistry and Biochemistry, University of Delaware  2. Department of Biological Science, University of Delaware

24.

Two-stage Biologically Interpretable Neural-network Models for Liver Cancer Prognosis Prediction Using Histopathology and Transcriptomic Data 

Zhucheng Zhan(1), Zheng Jing(2), Bing He(3), Noshad Hosseni(3), Maria Westerhoff(4)  Eun-Young Choi(4),  Lana X. Garmire(3)  1. Chinese University of Hong Kong  2. Department of Statistics, University of Michigan  3. Department of Computational Medicine and Bioinformatics, University of Michigan  4. Department of Pathology, University of Michigan, University of Michigan

26.

Survey of Structural Variants in 5,000 Multiple Myeloma Samples

James J. Kelley and Andrey Grigoriev*  Dept of Biology, Center of Computational and Integrative Biology, Rutgers University, Camden, NJ  * Correspondence Email: andrey.grigoriev@rutgers.edu  

27.

Investigating the Frequency of Copy Number Variants According to Ancestry in an Unselected Population

Alexys Knighton(1), Guillaume Huguet, PhD(2), Laura M. Schultz, PhD(3), Zohra Saci, PhD(2), Martineau Jean-Louis, PhD(2), Josephine Mollon, PhD(4), Emma Knowles, PhD(4), David Glahn, PhD (4), Sebastien Jacquemont, PhD (2), Laura Almasy, PhD (1,3)    1. University of Pennsylvania  2. University Hospital Center - Saint Justine  3. Department of Biomedical and Health Informatics at the Children's Hospital of Philadelphia  4. Boston Children's Hospital  

28.

Bioinformatic Analysis Reveals Possible Mechanisms of Aniridic Keratopathy 

Aarthi Krishnan, Adam P. Faranda, Samuel G. Novo, Yan Wang, MD, Melinda K. Duncan, PhD FARVO  

Department of Biological Sciences, University of Delaware

29.

FILER: Harmonized, Scalable Functional Genomics Repository and API

Pavel P. Kuksa(1), Prabhakaran Gangadharan(1), Lauren Kleidermacher(1,2), Živadin Katanić(1), Chien-Yueh Lee(1), Han-Jen Lin(1), Yi-Fan Chou(1), Emily Greenfest-Allen(1), Otto Valladares(1), Yuk Yee Leung(1), Li-San Wang(1)  1 Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania  2. Department of Biology, University of Pennsylvania

30.

A Generalizable Deep Learning Classifier Improves Somatic Variant Calling in Neuroblastoma

Lobin A Lee(1), John M Maris(1,2), Sharon J Diskin(1,2)  1. Genomics and Computational Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania; 2. Division of Oncology, Children's Hospital of Philadelphia

31.

Multi-ethnic Gene-trait Connection Landscape Using Electronic Health Record (EHR) Linked Biobank Data

Binglan Li (1), Anastasia Lucas (2), Yuki Bradford(2), Shefali S. Verma(2), Anurag Verma(2), Hae Kyung Im (3), Marylyn D. Ritchie(1,2,4)   1.Genomics and Computational Biology Program, University of Pennsylvania   2.Department of Genetics, University of Pennsylvania 3. Department of Medicine, The University of Chicago 4. Institute for Biomedical Informatics, University of Pennsylvania,

32.

Disease-specific Prioritization of Non-coding DNA Variants

Qianqian Liang, MS(1), Dennis Kostka, PhD(2)    1. Department of Human Genetics, University of Pittsburgh School of Public Health  2. Departments of Developmental Biology and Computational & Systems Biology, Pittsburgh Center for Evolutionary Biology and Medicine, University of Pittsburgh School of Medicine  

33.

A Pan-protease Cleavage Site Classifier for Machine Learning-based Encrypted Peptide Recognition

Jacqueline R.M.A. Maasch (Master's Candidate(1,2), Marcelo C. R. Melo, PhD, Postdoctoral Fellow(2), Cesar de la Fuente-Nunez PhD, Presidential Assistant Professor(2)    1. Department of Computer and Information Science, University of Pennsylvania School of Engineering and Applied Science  2. Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, Penn  Institute for Computational  Science,  and  Department  of  Bioengineering,  University  of  Pennsylvania

 

34.

Identification of Genes Influencing Human Subcortical Brain Structure by Using Tissue-specific Transcriptome Analysis

Hung Mai, Xiaohui Yao, Shan Cong, Li Shen  Department of Biostatistics, Epidemiology and Informatics

University of Pennsylvania Perelman School of Medicine

 

35.

Bioinformatic Discovery of miRNA Target Genes that Drive Inflammation in the Leukemic Bone Marrow

Linsey Zhang(1,3)*, Theresa Menna, BS (1)*, Zhe Zhang, PhD (2), Ding-Wen Chen, PhD (1), Peter Kurre, MD (1)    

1. Comprehensive Bone Marrow Failure Center, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, 2. Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, 3. Department of Biology, Swarthmore College

36.

Investigating Migraine and Mood Disorder Comorbidity in a Community-based Pediatric Sample

Alison K. Merikangas, MPH, PhD(1,2,3),  Rachel L. Kember, PhD(4),  Wei Guo, PhD(5),  Tarannum Lateef, MD, MPH(5,6),  Jian-Ping He, MSc(5),  Monica E. Calkins, PhD(2,4),  Ruben Gur, PhD(2,4),  Raquel Gur, MD, PhD(2,4),  Kathleen R. Merikangas, PhD(5),  Laura Almasy, PhD(1,2,3)    1. Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia 2. Lifespan Brain Institute of the Children's Hospital of Philadelphia and Penn Medicine  3. Department of Genetics, Perelman School of Medicine, University of Pennsylvania   4. Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania   5. Genetic Epidemiology Research Branch, Intramural Research Program, National Institute of Mental Health  6. Department of Neurology, Children's National Hospital  

37.

Single Cell Resolution Regulatory Landscape of the Kidney Highlights Cellular Differentiation Programs and Renal Disease Targets

Zhen Miao(1,2)#, Michael S. Balzer(1)#, Ziyuan Ma()1, Hongbo Liu(1), Mingyao Li, Junhyong Kim, Klaus Kaestner and Katalin Susztak(1)*  1.Renal, Electrolyte, and Hypertension Division, Department of Medicine, University of Pennsylvania, Perelman School of Medicine 2. Graduate Group in Genomics and Computational Biology, University of Pennsylvania, Perelman School of Medicine #Contributed equally; *Corresponding author  

38.

Genomic Characterization of RNA Granule-linked genes Using Large Biobanks

Jason E. Miller, PhD(1), Theodore G. Drivas, MD, PhD(2), Xinyuan Zhang(3), Anastasia Lucas(1), Maja Bucan, PhD(1),

Marylyn D. Ritchie, PhD(1,3)    1. Department of Genetics, Perelman School of Medicine, University of Pennsylvania   2. Children's Hospital of Philadelphia 3. Genomics and Computational Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania

39.

MicroRNA 5p and 3p Strands Mediate Coordinated Regulation and Recurrently Modulate Pan-tumor Oncogenic Pathways

Ramkrishna Mitra, Ph.D   Clare M. Adams, Ph.D   Christine M. Eischen, Ph.D    

Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA   

40.

Measuring Protein Structure Deviation Using Machine Learning

Ethan J. Moyer and Ahmet Sacan, Ph.D.

Drexel University, School of Biomedical Engineering, Science and Health Systems, Philadelphia, PA.

41.

Molecular Mechanisms and Functional Impact of Aberrant Splicing in Diffuse Midline Gliomas

Ammar S. Naqvi(1), Brian Ennis(1), Krutika S. Gaonkar(1), Yuankun Zhu(1),  Miguel A. Brown(1), Bo Zhang(1),  Phillip B. Storm(1,2), Adam C. Resnick(1), Jo Lynne Rokita(1) 1. Children's Hospital of Philadelphia, Center for Data-Driven Discovery in Biomedicine 2. Children's Hospital of Philadelphia,Division of Neurosurgery

42.

Genetic Variation and microRNA Targeting of A-to-I RNA Editing Fine Tune Human Tissue Transcriptomes

Eddie Park(1), Lili Hao(2), Yi Xing(3),    1.Center for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. 2.National Genomics Data Center & BIG Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China. 3.Center for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.   Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.  

43.

ARID1A Restricts Chromatin Accessibility and Histone H4 Acetylation in the Endometrial Epithelium

Reske JJ(1), Wilson MR1, Chandler RL(1,2)    1. Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University 2. Center for Epigenetics, Van Andel Research Institute, 

44.

Analysis of Genetic Variation, Gene and Protein Expression in Eosinophilic Esophagitis

Melanie A. Ruffner, MD, PhD(1,2),  Margaret C. Carroll(1),  Michele Meline(1),  Kathleen E. Sullivan MD, PhD(1,2), Jonathan M. Spergel, MD, PhD(1,2),  Patrick M. Sleiman, PhD(1,3)    1. University of Pennsylvania Perelman School of Medicine Department of Pediatrics  2. Children's Hospital of Philadelphia Division of Allergy and Immunology  3. Children's Hospital of Philadelphia Center for Applied Genomics

45.

Generative Modeling Approach for Computational Doublet Detection

Hannah C. Schriever(1),  Dennis Kostka, PhD(2), 1. Carnegie Mellon-University of Pittsburgh Computational Biology Department University of Pittsburgh School of Medicine   2. Departments of Developmental Biology and Computational & Systems Biology Pittsburgh Center for Evolutionary Biology and Medicine  University of Pittsburgh School of Medicine

46.

Association Between Polygenic Risk Scores Computed Across Ancestry Groups 

Laura M. Schultz, PhD(1), Raquel E. Gur, MD, PhD(2,3,4),  Alison K. Merikangas,MPH, PhD(1,3,5),  Monica E. Calkins,PhD(2,3),  Ruben C. Gur, PhD(2,3),  Tyler M. Moore, PhD(2,3),  Kosha Ruparel, MSE, MS(2,3),  Ran Barzilay,MD, PhD(2,3,4),  Laura Almasy, PhD(1,3,5)      1.Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia  2. Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania  3. Lifespan Brain Institute of the Children's Hospital of Philadelphia and Penn Medicine  4. Department of Child Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia  5. Department of Genetics, Perelman School of Medicine, University of Pennsylvania   

47.

Testing Genetic Interactions in Long-range High linkage Disequilibrium Regions Supports Epistasis and Potential Pleiotropy among Complex Diseases

Pankhuri Singhal, Shefali S. Verma, Alex Frase, Sudha Veturi, Marylyn D. Ritchie

University of Pennsylvania

48.

Pulmonary Nodules Detection on Chest x-ray: A Comparison of Artificial Intelligence and Radiologists with Gray Scale Inversion

Aylin Tahmasebi, Shuo Wang 1, Patrick Lee, Maansi R. Parekh, Jaydev K. Dave, Maruti Kumaran, John R. Eisenbrey, Achala Donuru  1. Department of Radiology, Thomas Jefferson University Hospital  

49.

Transcriptome Analysis of Families Reveals that Gene Expression  Variation is Influenced by the Presence of 16p12.1 Deletion and by  Family-specific variants / Integrative Analyses of Biological Data on Multiple Scales

Anastasia Tyryshkina PhD Candidate, Matthew Jenson PhD Candidate, Lucilla Pizzo PhD, Santhosh Girirajan MBBS, PhD   Department of Biochemistry and Molecular Biology, The Pennsylvania State University

50.

Predictive Modeling of Single-cell DNA Methylome Data Enhances Integration with Transcriptome Data

Yasin Uzun, PhD (1) Hao Wu, PhD (2) Kai Tan PhD(1) 1. Children's Hospital of Philadelphia 2. University of Pennsylvania   

51.

Cox-nnet v2.0: Improved Neural-network Based Survival Prediction Extended to Large-scale EMR Dataset

Di Wang (1), Kevin He, PhD(1),  Lana X Garmire, PhD(2) 1. Department of Biostatistics, University of Michigan 2. Department of Computational Medicine and Bioinformatics, University of Michigan

52.

PIONEER: Harnessing Multi-omics Data to Enhance Immunotherapeutic Target Discovery and Development

Amber K. Weiner BA (1),  Benjamin A. Garcia PhD (3), John M. Maris MD (1,2), Sharon J. Diskin PhD (1,2)    1. Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia 2. Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania  3. Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania

53.

A Joint Integrative View of the Regulatory and Transcriptional Landscapes in Human and Mouse Hematopoiesis

Guanjue Xiang, Belinda Giardine, Shaun Mahony, Yu Zhang, Ross C. Hardison

The Pennsylvania State University

54.

Using Deep Learning to Detect Pathology in Lateral View Chest X-rays

Jessica Yarnall, MS(1)  Benjamin Mitchell, PhD(2)

1.Villanova University 2.Swarthmore College

55.

Image-processing Based Detection of Architectural Stripes from Chromatin Conformation Data

Sora Yoon, PhD,  Maria Fasolino, PhD, Naomi Golaman, PhD student,  Wenliang Wang, PhD, Golnaz Vahedi, PhD, PhD, Department of Genetics, University of Pennsylvania Perelman School of Medicine